The study of the epidemiology of HIV and AIDS as an important component in the development of directions for the rational use of limited health resources and pharmaceutical provision of the population in Ukraine

Authors

DOI:

https://doi.org/10.24959/sphhcj.21.220

Keywords:

HIV; AIDS; HIV epidemiology; AIDS epidemiology; epidemiological profile of the population with HIV

Abstract

Aim. To study the indicators characterizing the epidemiological profile of the population of Ukraine concerning HIV and AIDS in the dynamics of the years.

Materials and methods. Data from the Center for Public Health of the Ministry of Health of Ukraine were used. Both general theoretical (historical, analytical-comparative, systemic, logical, etc.) and applied methods (epidemiological, mathematical-statistical, etc.) were applied.

Results. It was found that during 2015-2019 there was an increase in the rates of HIV infection of the population, both sexually and parenterally (excluding data for 2017). In 2019, the number of cases of human infection through sexual contact increased by 27.1 % compared to 2015, and via parenteral infection – by 31.4 %. The trend towards a systematic decrease in the number of children born to HIV-infected mothers during the entire follow-up period was positive. In 2019, compared with the data for 2015, there was an increase in the number of HIV-infected adults by 3.1 %, while AIDS patients, on the contrary, decreased by 11.3 %. An important fact was a decrease in the number of HIV-infected children under 18 by 27.3 % and children under 14 by 27.6 % in 2019 compared to 2015. A negative trend was an increase in the number of deaths from AIDS-related pathologies among adults in 2015-2018, as well as among children under 18 years of age in 2019 by 18.0 %. Based on the results of the analysis of the structure of HIV-infected people by age, there was a systematic increase in the proportion (%) of adults (from 81.0 % in 2015 to 86.6 % in 2019). In addition, the number of adult patients per HIV-infected child under the age of 18 was increasing (2015 – 4.27 adult patients, in 2016 – 4.98 people, in 2017 – 4.91 people, 2018 – 5.39 people, and 2019 – 6.68 people).

Conclusions. The presence of positive trends in the development of the epidemiological profile of the population of Ukraine for HIV and AIDS requires not only financial support from the state and society in the future, but also the development and implementation of the appropriate social and educational projects aimed at preventing further spread of this infection among the population.

References

Tumwebaze, F., Akakimpa, D., Kityo, C., Mugyenyi, P., Abongomera, G. (2018). Towards 90-90-90 Target : Factors Influencing Availability, Access, and Utilization of HIV Services – A Qualitative Study in 19 Ugandan Districts. BioMed Research International, 18. doi: https://doi.org/10.1155/2018/9619684.

The global HIV/AIDS epidemic-progress and challenges. (2017). The Lancet, 390 (10092), 333. doi: https://doi.org/10.1016/S0140-6736(17)31920-7.

Beloukas, A, Psarris, A, Giannelou, P, Kostaki, E, Hatzakis, A, Paraskevis, D. (2016). Molecular epidemiology of HIV-1 infection in Europe: An overview. Infect Genet Evol., 46, 180-189. doi: https://doi.org/10.1016/j.meegid.2016.06.033.

Castel, A. D., Magnus, M., Greenberg, A. E. (2015). Update on Epidemiology and Prevention of HIV/AIDS in the United States. Curr Epidemiol Rep., 2 (2), 110-119. doi: https://doi.org/10.1007/s40471-015-0042-8.

Yakob, B, Ncama, B. P. (2016). A socio-ecological perspective of access to and acceptability of HIV/AIDS treatment and care services: a qualitative case study research. BMC Public Health, 16, 155. doi: 10.1186/s12889-016-2830-6.

Zuma, T., Wight, D., Rochat, T., Moshabela, M. (2017). Traditional health practitioners’ management of HIV/AIDS in rural South Africa in the era of widespread antiretroviral therapy. Glob Health Action., 10 (1), 1352210. doi: 10.1080/16549716.2017.1352210.

Gari, S., Doig-Acuña, C., Smail, T., Malungo, J. R., Martin-Hilber, A., Merten, S. (2013). Access to HIV/AIDS care: a systematic review of socio-cultural determinants in low and high income countries. BMC Health Serv Res., 13, 198. doi: 10.1186/1472-6963-13-198.

Yakob, B, Ncama, B. P. (2016). Correlates of Strengthening Lessons from HIV/AIDS Treatment and Care Services in Ethiopia Perceived Access and Implications for Health System. PLoS One, 11 (8), e0161553. doi: 10.1371/journal.pone.0161553.

Schwitters, A., Lederer, P., Zilversmit, L. et al. (2015). Barriers to health care in Rural Mozambique: A rapid ethnographic assessment of planned mobile health clinics for ART. Global Health Science and Practice, 3 (1), 109–116. doi: https://doi.org/10.9745/GHSP-D-14-00145.

Epidemiia VIL-infektsii v Ukraini / Natsionalna vidpovid. Available at: https://unaids.org.ua/ua/hiv-epidemic-in-ukraine/derzhavna-programa-zi-snid.

Tsentr hromadskoho zdorovia MOZ Ukrainy. (n. d.) Statystychni dovidky pro VIL/SNID. Available at: https://www.phc.org.ua/kontrol-zakhvoryuvan/vilsnid/statistika-z-vilsnidu/statistichni-dovidki-pro-vilsnid.

Cakalo, J. I., Bozicevic, I., Vitek, C., Mandel, J. S., Salyuk, T. R. (2015). Misclassification of men with reported HIV infection in Ukraine. AIDS Behav, 19, 1938-1940. doi: https://doi.org/10.1007/s10461-015-1112-0.

Barska, Y., Sazonova, Y. (2016). Monitoring of behavior and HIV prevalence among people who inject drugs and their sexual partners: results of the 2015 study. Kyiv: Alliance of Public Health, 130. Available at: http://aph.org.ua/wp-content/uploads/2015/05/ Monitoryng-povedinky-SIN__Eng__Na-RED.pdf.

Country factsheets: Ukraine. (2019). Available at: https://www.unaids.org/en/regionscountries/countries/ukraine.

Degenhardt, L., Peacock, A., Colledge, S. et al. (2017). Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review. Lancet Glob Health, 5, e1192-e1207. doi: https://doi.org/10.1016/S2214-109X(17)30375-3.

Mazhnaya, A., Marcus, R., Boiko, M.J. et al. (2018). Opioid agonist treatment and improved outcomes at each stage of the HIV treatment cascade in people who inject drugs in Ukraine. J Acquir Immune Defic Syndr., 79 (3), 288-295. doi: https://doi.org/10.1097/QAI.0000000000001827.

Altice, F. L., Azbel, L., Stone, J. et al. (2016). The perfect storm : incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia. Lancet, 388 (10050), 1228-1248. doi: https://doi.org/10.1016/S0140-6736(16)30856-X.

Diachenko, A. H. et al. (2015). VICh-infektsyia (teoriia i praktika). Sumy: Sum. hos. un-t, 209.

Stepanovskyi, Yu. S. (2014). Klinichni ta imunolohichni kryterii prohnozuvannia perebihu VIL-infektsii u ditei. Candidate’s thesis. Kyiv.

Demchenko, I. et al. (2017). Monitorynh poinformovanosti, povedinky ta poshyrenosti VIL-infektsii ta inshykh sotsialno-nebezpechnykh zakhvoriuvan sered zasudzhenykh yak komponent epidnahliadu za VIL druhoho pokolinnia : analit. zvit za rezultatamy biopovedink. doslidzh. Kyiv: Feniks.

Balakirieva, O. (2017). Posylennia komponenta po roboti z pidlitkamy v ramkakh natsionalnoi prohramy VIL/SNID: advokatsiin. zvit za rezultatamy doslidzh. “Otsinka sytuatsii u kraini z metoiu posylennia komponenta po roboti z pidlitkamy v ramkakh natsionalnoi prohramy VIL/SNID”. Kyiv: Ukr. in-t sots. doslidzh. im. Oleksandra Yaremenka.

Balakirieva, O. (2015). Robota zi stratehichnoiu informatsiieiu u sferi protydii VIL-infektsii/SNIDu na rehionalnomu rivni. Kyiv: Polihraf plius.

Winter, J. R., Smith, C. J., Davidson, J. A., Lalor, M. K. et al. (2020). The impact of HIV infection on tuberculosis transmission in a country with low tuberculosis incidence : a national retrospective study using molecular epidemiology. BMC Medicine, 18, 385. doi: https://doi.org/10.1186/s12916-020-01849-7.

Fang, J.-Q. (Ed.). (2017). Handbook of Medical Statistics. China: Sun Yat-Sen University.

Published

2021-06-11

Issue

Section

Social marketing and pharmacoeconomic research