The analysis of the pharmaceutical market of antifungal drugs in Ukraine

Authors

  • O. Ye. Okseniuk State Institution “Lugansk State Medical University” Ministry of Health of Ukraine, Ukraine
  • O. P. Gudzenko State Institution “Lugansk State Medical University” Ministry of Health of Ukraine, Ukraine
  • O. S. Shpychak National University of Pharmacy, Ukraine https://orcid.org/0000-0002-3015-8584

DOI:

https://doi.org/10.24959/sphhcj.20.169

Keywords:

antifungal drugs for local use, pharmaceutical market, market analysis, market segment, price range

Abstract

Aim. To analyze the domestic pharmaceutical market of antifungal drugs for the local treatment of fungal skin lesions taking into account all drug forms.

Materials and methods. The analysis was carried out on the basis of data from the State Register of Medicines of Ukraine, electronic databases, the retrieval information program “Morion” and the price lists of the weekly publication “Apteka” as of March 10, 2019. The logical, system-based analytical, mathematical-statistical and comparative methods of analysis were used in our work.

Results. According to the results of the analysis of antifungal drugs for local use registered inUkraine (D01A group) it has been found that most of them are produced by foreign manufactures, and the share of domestic drugs is 41 %. In addition, the studies have shown that more than half of the drugs of the D01A group (54 %) registered are presented in soft medicinal forms (creams, ointments and gels), and 30 % are drugs in the form of solutions, where 8 % are sprays. The trade names of the active substances (terbinafine, clotrimazole, ketoconazole, naphthine and salicylic acid) presented mainly in greatest quantity have been determined. It has been found that among the drugs registered 91 % are monocomponent ones. The distribution of the assortment of drugs of the group “D01A E - Other Antifungal Drugs for Local Use” has been divided into price categories, and their lower, middle and high prices have been determined. Using the pricing method for developing drugs with the focus on competitive prices it has been determined that the most profitable position is in the middle price category.

Conclusions. The results of the market research can be used to develop practical measures to increase the efficiency of implementing socially adapted mechanisms for reimbursement of the cost of consumption of antifungal drugs as a part of the government measures to increase the availability of pharmaceutical care for patients in Ukraine.

References

Vlasenko, I. O., Dullakh, Aram, Davtian, L. L. (2013). Farmatsevtychnyi zhurnal, 6, 16–24.

Kovalenko, V. L., Nesterenkova, V. V., Kovalenko, L. I., Mandyhra, M. S. (2014). Veterynarna biotekhnolohiia, 24, 64–71. Available at: http://nbuv.gov.ua/UJRN/vbtb_2014_24_13 (Accessed : 25.11.2019).

Korolenko, V. V. (2010). Ukrainskyi zhurnal dermatolohii, venerolohii, kosmetolohii, 3 (38), 109-116.

Tichonov, A. I., Jarnych, T. G., Czernych, W. P. et al. (2005). Teoria i praktyka wytwarzania leczniczych preparatow propolisowych. Khrakov: Marka, 274.

Thappa, D. M. (2007). Current treatment of onychomycosis. Ind. J. of Dermatol., Venereol. and Leprol., 73 (6), 373–376.

Тikhonov, О. І., Frolova, О. E., Shpychak, O. S. (2016). Creation of pharmaceutical compositions with the antifungal, antimicrobial and keratolytic activity. Clinical Pharmacy, 20 (3), 54-59.

Frolova, O. Ye., Tikhonov, O. I., Shpychak, О. S., Novikov, S. M., Lenchin V. M. (2016). Development of the technology of vials-pencils for storage and application of medicated products on the skin and its appendages. The Pharma Innovation Journal, 5 (10), 43-48.

Baza dannykh “Lekarstvennye sredstva” OOO “Morion”. Available at: www.morion.kiev.ua (Accessed: 25.11.2019).

Derzhavnyi reiestr likarskykh zasobiv. On-line versiia. Available at: http://www.moz.gov.ua/ua/portal/mtph_register_medicines/ (Accessed: 25.11.2019).

Derzhavnyi formuliar likarskykh zasobiv. Vypusk vosmyi. (2016). Kyiv. Available at: http://www.dec.gov.ua/index.php/ua/informatsijno-poshukova-sistema-elektronnij-formulyar/ (Accessed: 25.11.2019).

Kovalenko, V. N. (Ed.). (2017). Kompendium 2016 – Lekarstvennye preparaty. Kyiv: MORION, 2270.

Doddanna, S. J., Patel, S., Sundarrao, M. A., Veerabhadrappa, R. S. (2013). Antimicrobial activity of plant extracts on Candida albicans: An in vitro study. Indian J Dent Res., 24 (4), 401–405. doi: 10.4103/0970-9290.118358.

Gupta, A. K., Simpson, F. C. (2012). New therapeutic options for onychomycosis. Expert Opin. Pharmacother, 13 (8), 1131–1142. doi: 10.1517/14656566.2012.681779.

Kratzer, C., Tobudic, S., Assadian, O., Buxbaum, A., Graninger, W., Georgopoulos, A. (2006). Validation of Akacid plus as a room disinfectant in the hospital setting. Applied аnd Environmental Microbiology, 72 (6), 3826–3831. doi: 10.1128/AEM.00379-06.

Lain, N., Ascanio, R., Baker, C. et al. (2000). Undecylenic acid inhibits morphogenesis of Candida albicans. Antimicrob. Agents Chemother, 44 (10), 2873–2875.

Dmitrik, E. (2017). Ezhenedelnik apteka, 2 (1073). Available at: http://www.apteka.ua/article/398728 (Accessed: 25.11.2019).

Dmitrik, E. (2017). Ezhenedelnik apteka, 4 (1075). Available at: http://www.apteka.ua/article/400102 (Accessed: 25.11.2019).

Mnushko, Z. M., Timaniuk, I. V., Pestun, I. V., Skrylova, N. M. (2009). Zaporozhskyi medytsynskyi zhurnal, 11 (2), 83-87. Available at: http://nbuv.gov.ua/UJRN/Zmzh_2009_11_2_27 (Accessed: 25.11.2019).

Tymchuk, I. V., Kutsyk, R. V., Danyleichenko, V. V., Korniichuk, O. P. (2014). Acta medica Leopoliensia, 20 (1), 88-94. Available at: http://nbuv.gov.ua/UJRN/Lmch_2014_20_1_18 (Accessed: 25.11.2019).

Frolova, O. Ye., Hudzenko, O. P., Tykhonov, O. I., Shpychak, O. S. (2016). Ukrainskyi zhurnal klinichnoi ta laboratornoi medytsyny, 11 (3), 77-80.

Downloads

Published

2020-03-10

Issue

Vol. 6 No. 1 (2020)

Section

Social marketing and pharmacoeconomic research

License

Copyright (c) 2020 National University of Pharmacy

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).