The analysis of the range of antipsoriatic medicines used in the local treatment of mild psoriasis in Ukraine
uk.
DOI:
https://doi.org/10.24959/sphhcj.21.211Abstract
Today, according to various authors, the prevalence of psoriasis is 12-15% of the total number of skin diseases. The incidence of psoriasis in countries with high economic development is 1.5-2%. Therefore, the development of new drugs for the treatment of psoriasis is an urgent problem of domestic pharmacy.
Aim. To analyze the range of antipsoriatic drugs used in the local treatment of mild psoriasis in Ukraine.
Materials and methods. The assortment of drugs was analyzed in accordance with the State Registry of Medicines of Ukraine and the АТС classification system. In the course of the research, the content analysis and the analysis of scientific information using internet sources on the selected topic were performed; analytical and statistical methods of analysis were applied.
Results. According to the retrospective analysis, there is a constant change in the ratio of domestic and foreign producers during the study period.
It has been determined that 17.5 % are occupied by semisolid dosage forms; cream (10.0 %), paste (5.0 %) and gel (2.5 %) are the closest in the form to the drug proposed for introduction.
The analysis of dermatological drugs compared to the analogs has allowed us to determine that there are 8 trade names at the domestic pharmaceutical market. Among them, 75.0 % have a synthetic component, while 25.0 % are combined preparations (herbal components and synthetic composition)
Conclusions. The range of antipsoriatic drugs in the local treatment of mild psoriasis has been analyzed in the article. In recent years, the research on the treatment of this disease has been actively conducted due to the large number of patients. There is a need to develop new effective domestic anti-psoriatic drugs. It is advisable to carry out further development of new drugs of the combined composition for the treatment of mild psoriasis.
Key words: antipsoriatic medicines; assortment analysis; forms of psoriasis; local treatment.
References
Havryliuk, A. A. (2015). Visnyk VDNZU “Ukrainska medychna stomatolohichna akademiia”, 1 (3 (51)), 300–303.
Fedorenko, O. Ye. (2012). Ukrainskyi zhurnal dermatolohii, venerolohii, kosmetolohii, 1 (44), 59–62.
Kharchenko, T. (2012). Ukrainskyi medychnyi chasopys, 4, 112–116.
Problematika psoriaza v Ukraine i v mire v 2019 godu. Ukrainskaia Assotciatsiia Psoriaza. Available at: https://www.ukrinform.ru/rubric-presshall/2807308-problematika-psoriaza-v-ukraine-i-v-mire-v-2019-godu.html
Kotvitska, A. A., Karlo, V. V. (2013). Zaporozhskyi medytsynskyi zhurnal, 3 (78), 38–42. doi: https://doi.org/10.14739/2310-1210.2013.3.13569.
MOZ Ukrainy. (2015). Nakaz vid 20.11.2015 No. 762 “Pro zatverdzhennia ta vprovadzhennia medyko-tekhnolohichnykh dokumentiv zi standartyzatsii medychnoi dopomohy pry psoriazi, vkliuchaiuchy psoriatychni artropatii”. ips.ligazakon.net. Available at: https://ips.ligazakon.net/document/MOZ25270.
zhovtnia 2019 roku – Mizhnarodnyi den psoriazu : infor. lyst 25.10.2019 Kharkiv. obl. tsentr zdorovia. Available at: http://khocz.com.ua/29-zhovtnja-2019-roku-mizhnarodnij-den-psoriazu/.
Shulenina, O. (2017). Psoriaz v tsyfrakh. Available at: https://www.bsmu.edu.ua/blog/6212-psoriaz-v-tsifrah/.
MKB 10 – Mezhdunarodnaia klassifikatciia boleznei 10-go peresmotra. Available at: https://mkb-10.com/index.php?pid=11138.
Taranenko, Yu. S., Hladukh, Ye. V. (2021). Débats scientifiques et orientations prospectives du développement scientifique: collection de papiers scientifiques «ΛΌГOΣ» avec des matériaux de la I conférence scientifique et pratique internationale. (5 février 2021). (Vol. 6.). (pp. 103–104). Vinnytsia; Paris: Plateforme scientifique européenne & La Fedeltà. Available at: https://ojs.ukrlogos.in.ua/index.php/logos/issue/view/05.02.2021/440.
Yemchenko, Ya. O., Ishcheikin, K. Ye., Kaidashev, I. P. (2019). Visnyk problem biolohii i medytsyny, 2 (2 (151)), 33–38.
Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy. Psoriaz, vkliuchaiuchy psoriatychni artropatii. (2015). Available at: https://dec.gov.ua/wp-content/uploads/images/dodatki/2015_762_psoriaz/2015_762_YKPMD_psoriaz.pdf.
Kompendium – lekarstvennye preparaty. Available at: https://compendium.com.ua/.
Derzhavnyi reiestr likarskykh zasobiv Ukrainy. Available at: http://www.drlz.com.ua/.
Psoriaz: mify i realnost. (2018). Ezhenedelnik Apteka. Available at: https://www.apteka.ua/article/469403.
Downloads
Published
Issue
Section
License
Copyright (c) 2021 National University of Pharmacy
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
