The study of the effect of adherence with modern recommendations on antihypertensive therapy on compliance of patients with arterial hypertension
DOI:
https://doi.org/10.24959/sphhcj.22.248Keywords:
Сompliance; arterial hypertension; antihypertensive therapy; fixed dose combinations.Abstract
Aim. To study the relationship between the adherence with modern recommendations on antihypertensive therapy using fixed combinations of drugs in a “single” tablet with patients’ compliance and suggest ways to improve compliance in patients with hypertension based on the data obtained.
Materials and methods. Compliance of patients was assessed using the compliance scale of Hill-Bone arterial hypertension therapy; the nature of the antihypertensive therapy received was analyzed.
Results. Compliance of hypertensive patients was 63.64 %. No patients with low compliance and no compliance at all were found among the patients examined. Female patients had 1.32 times more compliance for treating hypertension than male patients. At the same time, only 36.11 % of patients received a fixed combination of drugs in a “single” tablet. It was found that in patients receiving monotherapy with an antihypertensive drug, compliance was 60 %; in patients receiving combination therapy with several drugs compliance was 68.75 %, while compliance of patients receiving fixed combinations of antihypertensives was 71.43 %.
Conclusions. The results obtained indicate a relatively low level of compliance in patients with hypertension. Also, against the background of insufficient adherence with current recommendations on antihypertensive therapy, a significantly higher compliance of patients treated with fixed combinations of antihypertensive drugs in a “single” tablet has been determined.
References
Servier. (2021). “Servier” sovmestno s Mezhdunarodnym obshchestvom arterialnoi gipertenzii zapustili novuiu volnu informatcionno-prosvetitelskoi kampanii #potomuchtotaknado. Available at: https://servier.ru/servier-i-ish-zapustili-novuyu-volnu-informatsionno-kampanii-potomuchtotaknado/#_ftnref2.
Arterialna hipertenziia. Klinichna nastanova. Available at: https://dec.gov.ua/wp-content/uploads/2019/11/kn_artergipert.
Klinicheskie protokoly diahnostiki i lecheniia serdechno-sosudistyh zabolevanii. Available at: https://www.minzdrav.uz/documentation/detail.php?ID=41771.
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M. et al. (2018). ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. Journal of Hypertension, 36 (10), 1953-2041. doi: https://doi.org/10.1097/HJH.0000000000001940.
Pasiechko, N., Radetska, L., Yarema, N., Bob, A., Smatchylo, I., Homitska, A. (2019). Zdobutky klinichnoi i eksperymentalnoi medytsyny, 1, 112-116. doi: https://doi.org/10.11603/1811-2471.2019.v0.i1.10059.
Katerenchuk, I. P., Mokhnachov, O. V. (2019). Visnyk problem biolohii i medytsyny, 2 (2), 120-123. doi: https://doi.org/10.29254/2077-4214-2019-2-2-151-120-123.
Burnier, M. (2017). Drug adherence in hypertension. Pharmacological Research, 125, 142-149. doi: https://doi.org/10.1016/j.phrs.2017.08.015.
Burnier, М., Egan, B. M. (2019). Adherence in Hypertension. Circulation Research, 124 (7), 1124-1140. doi: https://doi.org/10.1161/CIRCRESAHA.118.313220.
Lima, D., Moreira, T., Borges, J., Rodrigues, M. (2016). Аssociation between treatment compliance and different types of cardiovascular complications in arterial hypertension patients. Texto & Contexto - Enfermagem, 25 (3). doi: https://doi.org/10.1590/0104-07072016000560015.
Tykhonova, S. A., Shtanko, V. A. (2019). Visnyk naukovykh doslidzhen, 2, 114-117. Available at: http://repo.odmu.edu.ua:80/xmlui/handle/123456789/5674.
Iancu, M., Mateiciuc, I., Stanescu, A., Matei, D., Diaconu, C. (2020). Therapeutic Compliance of Patients with Arterial Hypertension in Primary Care. Medicina, 56 (11), 631. doi: https://doi.org/10.3390/medicina56110631.
Unger, T., Borghi, C., Charchar, F., Khan, N., Poulter, N., Prabhakaran, D. et al. (2020). International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension, 75 (6), 1334-1357. doi: https://doi.org/10.1161/HYPERTENSIONAHA.120.15026.
Likuvannia arterialnoi hipertenzii: maibutnie – za fiksovanymy kombinatsiiamy. (2019). Apteka, 36. Available at: https://www.apteka.ua/article/515181.
Carl, T. (2021). The Hill-Bone Scales Confirmation. nursing.jhu.edu. Available at: https://nursing.jhu.edu/faculty_research/research/projects/hill-bone/hill-bone-scales-confirmation.html.
Zeller, A., Schroeder, K., Peters, T. (2008). An adherence self-report questionnaire facilitated the differentiation between nonadherence and nonresponse to antihypertensive treatment. Journal of Clinical Epidemiology, 61 (3), 282-288. doi: https://doi.org/10.1016/j.jclinepi.2007.04.007.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 National University of Pharmacy
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
