The current state and the development prospects of the ukrainian market of antihistamines




allergic diseases, pharmaceutical market, antihistamines


Nowadays allergy has become a global problem for all humanity. According to the WHO about 30-40 % of the world’s population suffers from allergic diseases. Environment pollution, as well as everyday use of a large number of synthetic substances, contribute to the rapid increase in incidence of allergic reactions. The therapy of these diseases is based mainly on the antihistamine drugs (AHD), which makes it reasonable to study the Ukrainian market of AHD and to identify its promising directions of development.

Aim. To study the assortment of antihistamine drugs registered in Ukraine.

Materials and methods. The analysis was based on the official sources of information and materials of the previous marketing research using the methods of systematic, graphical and comparative analysis with the subsequent obtaining of explanations and conclusions.

Results. During the analysis of the domestic pharmaceutical market regarding the assortment of antihistamines it has been found that 128 drugs are used in Ukraine for the treatment of allergic diseases. The study of distribution by dosage forms has revealed the prevalence of solid dosage forms – tablets and dragee – their percentage is 71 %. The analysis of AHD by the manufacturing countries has shown the import dependence of the Ukrainian market: the foreign manufacturers represent 61 % of the drugs. Moreover, in recent years there is a downward trend of the share of domestic manufacturers (50 % – in 2014; 39 % – in 2019). India is the largest importer of antihistamines at the market (17.2 %); the total market share of the European Union countries is 39 %. The analysis of the current state of the pharmaceutical market has determined a change in the distribution of AHD by INN in favor of the new-generation drugs. The study has revealed the absence of anti-allergic herbal medicines in Ukraine; it substantiates the development of new drugs for the phytotherapy of allergic diseases.

Conclusions. The absence of plant-based anti-allergic drugs at pharmaceutical market of Ukraine has been found. Taking into account an increasing popularity of herbal medicines and growing demand for drugs with a good safety profile we have concluded that the development of a new plant-based drug for the allergy treatment is a topical direction for further studies.

Author Biographies

O. V. Andryushayev, National University of Pharmacy

postgraduate student of the Department of Industrial Technology of Drugs

О. A. Ruban, National University of Pharmacy

Doctor of Pharmacy (Dr. habil.), professor, head of the Department of Industrial Technology of Drugs

Yu. S. Masliy, National University of Pharmacy

Candidate of Pharmacy (Ph. D), associate professor of the Department of Industrial Technology of Drugs

L. V. Iakovlieva, National University of Pharmacy

Doctor of Pharmacy (Dr. habil.), professor, head of the Department of Pharmacoeconomics


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Social marketing and pharmacoeconomic research